CFI02 CAS No.:273735-28-7

Price:
Negotiable
minimum:
Total supply:
Delivery term:
The date of payment from buyers deliver within days
seat:
Jiangsu
Validity to:
Long-term effective
Last update:
2023-06-30 18:03
Browse the number:
345

Send an inquiries

Company Profile

Suzhou Ureiko Medical Chemistry Technology Co.,Ltd.

By certification [File Integrity]

Contact: youruike(Mr.)

Email:

Telephone:

Phone:

Area: Jiangsu

Address: Jiangsu

Website: http://www.ureiko-chem.com/ http://youruike.auto-hid.com/

Product details

Chemical Structure : CFI02

CAS No.: 273735-28-7

CFI02(CFI 02;CFI-02)

Catalog No.: URK-V2341Â Â Only Used For Lab.

CFI02 (CFI-02) is a specific inhibitor of human cytomegalovirus (HCMV) glycoprotein B-mediated fusion with IC50 of 40 nM against laboratory adapted HCMV strain AD169.

Biological Activity

CFI02 (CFI-02) is a specific inhibitor of human cytomegalovirus (HCMV) glycoprotein B-mediated fusion with IC50 of 40 nM against laboratory adapted HCMV strain AD169; reduces HCMV yield by >3 logs at 1 uM, and shows no inhibitory activity against closely related betaherpesviruses (including MCMV, simian CMV, and RCMV) (IC50>20 uM) as well as cytotoxic effect (CC50>50 uM).

Physicochemical Properties

M.Wt	491.43
Formula	C18H11F6N5OS2
CAS No.	273735-28-7
Storage	Solide Powder -20 Â°C 3years; 4Â°C 2years	In Solvent -80Â°C 6 Months -20Â°C 1 Months
Solubility	10 mM in DMSO
Chemical Name	N-(4-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)phenyl)-1,2,3-thiadiazole-4-carboxamide

References

1. Jones TR, et al. J Virol. 2004 Feb;78(3):1289-300.

2. Bloom JD, et al. Bioorg Med Chem Lett. 2003 Sep 1;13(17):2929-32.

URK-V2341_COA

URK-V2341_SDS

URK-V2341_TDS

Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!

http://www.ureiko-chem.com/